UW Drug Discovery and Development and Fee-for-Service Capabilities

The University of Wisconsin –Madison’s academic and scientific environment extends its infrastructure and expertise to business and industry. Join other Wisconsin and US clients and find a solution to advance your business needs with contracted development at UW.

Explore our areas of expertise and contact OCR by phone: 1-877-OCR-WISC (1-877-627-9472) or email: inquiries@ocr.wisc.edu.

  • High Throughput Screening and Medicinal Chemistry »

    • HTS of drug-like chemical libraries and human RNAi libraries
    • Biological profiling assays and mechanism of action assays
    • Molecular modeling and virtual screening
    • Mycoplasma detection in cultured cells
    • Training and access to liquid handling robotics. LiCor scanner and plate readers
    • Molecular modeling and virtual screening
  • Flow Cytometry »

    • Single cell analysis
    • Single cell sorting: single cell deposition and bulk sorting of live cells
    • Comprehensive assay services: sample prep, data acquisition and analysis for immunophenotyping, cell cycle, DNA content, apoptosis, phagocytosis, calcium flux, cytokine and phosphoprotein detection, mitochondrial membrane potential, oxidative burst
  • Histology/Pathology »

    • Microtomy and cryo sectioning; H&E and special stains
    • IHC protocol development and optimization
    • Expert “in house” pathology consultation
    • Histologic staining methods to histopathologic assays
    • DNA/RNA isolation, quantitative real time RT-PCR analysis
    • Standardized IHC/IF/ISH through automation
    • Multispectral imaging system NuanceTM (manual) and VectraTM (automated) imaging
  • Pharmacology »

    • Sample acquisition
    • Pharmacokinetic analytical assays
    • Pharmacogenetic assays
    • Pharmacodynamic assays
    • Preclinical Analytic services
  • Formulation and Characterization »

    • Drug, biologic and excipient physical/chemical characterization (pre-formulation)
    • Formulation
    • Analytical method development and validation
    • Stability testing
    • Structural elucidation
  • Biomanufacturing »

    • Plasmid DNA Production
    • Recombinant Protein Production
    • Cell Therapeutics Production
    • Viral Vector/Vaccine Production
    • Aseptic Fill/Finish
  • Human Blood/Tissue Biobank »

    • Isolation of human blood RNA and DNA
    • RNA, DNA, and protein sample quality determination
    • Human tissue sectioning, frozen or paraffin-embedded
    • Quantitative morphometric analysis with AQUA, Vectra, Nuance instruments
    • Laser capture microdissection; and PCR and quantitative RT PCR analyses.
    • Consultation for histologic services
  • Small Animal Imaging »

    • Noninvasive, high-resolution in-vivo and ex-vivo
    •  2-D and 3-D image viewing
    • microCT and micro MRI (anatomical and functional)
    • microPET and optical imaging (functional)
    • Intraoperative Real Time Near-Infrared optical imaging (functional)
    • Imaging of targeted, non-targeted, vascular, and activatable contrast agents

UW Innovation in Action

What is found through the deciphering of the carrots’ genetic code?

A recent public-private project dug deep, into the genome of carrots. And as researchers were able to sequence genomes, their work may also make an impacts on carrots and other crops that could improve health and economic outcomes in other nations. More.

Madison-made electrolyte going big at global battery manufacturer

The idea started more than 12 years ago as a hallway conversation between two UW-Madison researchers. Now, years later, startup Madison-based Silatronix has a Japanese manufacturer taking its work towards full production, an expansion is planned in Madison, and the industry paying close attention to their innovation.  More.

Innovative UW master’s program links science, business and law

Biotech is big, and UW-Madison’s M.S. in Biotechnology program is paving the way for other institutions with its avant-garde curriculum. The program’s cross-disciplinary approach prepares students in a wide variety of fields to be leaders of promising new technologies that are penetrating all sectors of the economy. More.

OCR Events Calendar connect to entrepreneurial resources

About OCR

The Office of Corporate Relations is strategically positioned within the Chancellor’s Economic Development Team. Our mission is to help businesses of all sizes connect to the resources of UW–Madison. We help solve business challenges, create new products, and help to grow the economy. Contact us with your question.

Contact Us

UW–Madison Office of Corporate Relations
455 Science Drive, Suite 230
Madison, WI 53711-1077

Phone: 1-877--OCR-WISC (1-877-627-9472)
Fax: 608-263-2841
Email: inquiries@ocr.wisc.edu