University of Wisconsin–Madison

UW Drug Discovery and Development and Fee-for-Service Capabilities

The University of Wisconsin –Madison’s academic and scientific environment extends its infrastructure and expertise to business and industry. Join other Wisconsin and US clients and find a solution to advance your business needs with contracted development at UW.

Explore our areas of expertise and contact OCR by email or phone: 1-877-OCR-WISC (1-877-627-9472).

  • High Throughput Screening and Medicinal Chemistry »

    • HTS of drug-like chemical libraries and human RNAi libraries
    • Biological profiling assays and mechanism of action assays
    • Molecular modeling and virtual screening
    • Mycoplasma detection in cultured cells
    • Training and access to liquid handling robotics. LiCor scanner and plate readers
    • Molecular modeling and virtual screening
  • Flow Cytometry »

    • Single cell analysis
    • Single cell sorting: single cell deposition and bulk sorting of live cells
    • Comprehensive assay services: sample prep, data acquisition and analysis for immunophenotyping, cell cycle, DNA content, apoptosis, phagocytosis, calcium flux, cytokine and phosphoprotein detection, mitochondrial membrane potential, oxidative burst
  • Histology/Pathology »

    • Microtomy and cryo sectioning; H&E and special stains
    • IHC protocol development and optimization
    • Expert “in house” pathology consultation
    • Histologic staining methods to histopathologic assays
    • DNA/RNA isolation, quantitative real time RT-PCR analysis
    • Standardized IHC/IF/ISH through automation
    • Multispectral imaging system NuanceTM (manual) and VectraTM (automated) imaging
  • Pharmacology »

    • Sample acquisition
    • Pharmacokinetic analytical assays
    • Pharmacogenetic assays
    • Pharmacodynamic assays
    • Preclinical Analytic services
  • Formulation and Characterization »

    • Drug, biologic and excipient physical/chemical characterization (pre-formulation)
    • Formulation
    • Analytical method development and validation
    • Stability testing
    • Structural elucidation
  • Biomanufacturing »

    • Plasmid DNA Production
    • Recombinant Protein Production
    • Cell Therapeutics Production
    • Viral Vector/Vaccine Production
    • Aseptic Fill/Finish
  • Human Blood/Tissue Biobank »

    • Isolation of human blood RNA and DNA
    • RNA, DNA, and protein sample quality determination
    • Human tissue sectioning, frozen or paraffin-embedded
    • Quantitative morphometric analysis with AQUA, Vectra, Nuance instruments
    • Laser capture microdissection; and PCR and quantitative RT PCR analyses.
    • Consultation for histologic services
  • Small Animal Imaging »

    • Noninvasive, high-resolution in-vivo and ex-vivo
    •  2-D and 3-D image viewing
    • microCT and micro MRI (anatomical and functional)
    • microPET and optical imaging (functional)
    • Intraoperative Real Time Near-Infrared optical imaging (functional)
    • Imaging of targeted, non-targeted, vascular, and activatable contrast agents

UW Innovation in Action

GE Researcher seated at a computer

A relationship with real world benefits for patients and Wisconsin

A multi-decade relationship between UW–Madison and GE Healthcare has created a stream of medical imaging inventions that look inside the human body with increasing accuracy.

UW-Madison professional development course boosts output for Wausau manufacturer

When the operations director at JARP Industries signed up for a lean operations course at UW-Madison, he wasn’t expecting the impact it would deliver. Learn how the course shaped plant manufacturing practices and updated workflow, output and efficiency. More.

Photo of a basketball hoop

UW awarded second research grant from NBA and GE Healthcare

The latest grant will support research looking at the prevention and treatment of hamstring injuries. And while the focus will be on the elite athletes, the knowledge will benefit everyone who takes the court. More.

More of UW in Action

OCR Events Calendar UW-Madison Business Engagement Day on Campus