University of Wisconsin–Madison

UW Drug Discovery and Development and Fee-for-Service Capabilities

The University of Wisconsin–Madison’s academic and scientific environment extends its infrastructure and expertise to business and industry. Join other Wisconsin and US clients and find a solution to advance your business needs with contracted development at UW.

Explore our areas of expertise and contact OCR by email or phone: 1-877-OCR-WISC (1-877-627-9472).

The UW Carbone Cancer Center Drug Discovery Core (DDC) »

  •     Facilitates cancer-related preclinical drug discovery
  •     Integrates high throughput screening, medicinal chemistry, pharmocology.

Small Molecule Screening Facility   |    Cancer Pharmacology Lab   |   Medicinal Chemistry

    Flow Cytometry »

  •         Single cell analysis
  •         Single cell sorting: single cell deposition and bulk sorting of live cells
  •         Comprehensive assay services: sample prep, data acquisition and analysis for immunophenotyping, cell cycle, DNA content, apoptosis, phagocytosis, calcium flux, cytokine and phosphoprotein detection, mitochondrial membrane potential, oxidative burst

 Histology/Pathology »

  •         Microtomy and cryo sectioning; H&E and special stains
  •         IHC protocol development and optimization
  •         Expert “in house” pathology consultation
  •         Histologic staining methods to histopathologic assays
  •         DNA/RNA isolation, quantitative real time RT-PCR analysis
  •         Standardized IHC/IF/ISH through automation
  •         Multispectral imaging system NuanceTM (manual) and VectraTM (automated) imaging

    Formulation and Characterization »

  •         Drug, biologic and excipient physical/chemical characterization (pre-formulation)
  •         Formulation
  •         Analytical method development and validation
  •         Stability testing
  •         Structural elucidation

 Biomanufacturing »

  •         Plasmid DNA Production
  •         Recombinant Protein Production
  •         Cell Therapeutics Production
  •         Viral Vector/Vaccine Production
  •         Aseptic Fill/Finish

  Small Animal Imaging »

  •         Noninvasive, high-resolution in-vivo and ex-vivo
  •          2-D and 3-D image viewing
  •         microCT and micro MRI (anatomical and functional)
  •         microPET and optical imaging (functional)
  •         Intraoperative Real Time Near-Infrared optical imaging (functional)
  •         Imaging of targeted, non-targeted, vascular, and activatable contrast agents

UW Innovation in Action

New center to help UW-Madison and others to the next generation of crop breeding and plant genetics

Wisconsin Crop Innovation Center (WCIC) is a 100,000-square-foot facility—with labs, greenhouses and growth chambers—poised to be the home to future plant biotechnology achievements. More.

UW resources help one of Wisconsin’s top manufacturers find continued success

Three times named Wisconsin manufacturer of the year, Greenheck continues to turn to UW-Madison business resources to help refine and improve their processes. More how that is shaping their success.

 

Gloved hands manipulate a skinlike material in a labratory setting

Made-in-Madison skin replacement starts final clinical trial for burn victims

Stratatech, a UW-Madison spinoff, aims to prove to the Food and Drug Administration that its material, called StrataGraft, is safe and effective for treating severe burns. More.

More of UW in Action

OCR Events Calendar